chemical and biological properties of trachyspermum ammiencapsulated in gelatin nanofilms

نویسندگان

somayeh jahani infectious diseases and tropical medicine research center, zahedan university of medical sciences, zahedan, ir iran

gholamreza kavoosi institute of biotechnology, shiraz university, shiraz, ir iran

amin shakiba institute of biotechnology, shiraz university, shiraz, ir iran; institute of biotechnology, shiraz university, p. o. box: 71441-65186, shiraz, iriran. tel: +98-5413229792, fax: +98-5413229792

چکیده

results gelatin films exhibited good tensile strength and elongation at break, water solubility, swelling, and water vapor permeability. incorporation of tam into the gelatin films caused a significant decrease in tensile strength and swelling, and a significant increase in elongation at break, water solubility, water vapor permeability and whiteness of the films. gelatin films exhibited low antioxidant activity while gelatin films incorporated with tam exhibited excellent antioxidant properties. the films incorporated with tam also exhibited excellent antibacterial properties against both gram-positive and gram-negative bacteria. conclusions our results suggest that the gelatin/ta films could be used as a very attractive alternative to traditional materials for different biomedical applications. background development of biodegradable and biocompatible films based on the protein polymer with strong antibacterial activities is gradually obtained extensive concern in the world. objectives in this study, improvement of chitosan film properties incorporated with trachyspermum ammiessential oil as a potential antioxidant/antibacterial wound dressing was investigated. materials and methods gelatin films were prepared from gelatin solutions (10% w/v) containing trachyspermum ammiessential oil tam (2, 4, 6 and 8% w/w), glycerol (25% w/w) as plasticizer, and glutaraldehyde (2% w/w) as cross-linker. the mechanical, water solubility, water swelling, water vapor permeability, antioxidant and antibacterial properties of the films were measured according to the american society for testing and materials.

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عنوان ژورنال:
international journal of infection

جلد ۱، شماره ۱، صفحات ۰-۰

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